Key progress in key technologies for freeze-drying

China Drying Network was jointly developed by the Institute of Hygiene and Environmental Medicine of the Academy of Military Medical Sciences, the Experimental Instrument Factory, and Beijing Sihuan Science Instrument Factory Co., Ltd., and was awarded the "Development and Application of Intelligent Freeze Dryer Series". prize. The project is based on the cutting-edge of freeze-drying technology and combines high-efficiency and environmentally-friendly refrigeration systems. It has completed a number of independent innovation technologies and expanded its application and extension.

At the media symposium held by the Academy of Military Medical Sciences on the 30th, senior engineer Jiang Jianhua of the project said that the members of the project team have developed multi-functional monitoring software for 25 years and realized real-time remote data collection and tracking of freeze-dried data. As well as the real-time monitoring of the freeze-drying process, a highly efficient, green and environmentally friendly single-machine hybrid refrigeration system was developed. Established for the first time in the country to determine the eutectic point of the material on the basis of the combination of the material impedance value and the impedance change rate; establish the precise control of the vacuum degree by the infiltration method, and increase the freeze-drying efficiency by about 30%; establish the vacuum degree and the shelf temperature Freeze-drying endpoint online determination method combined with material temperature; establishment of precise control technology for multi-layer shelf temperature under complex environmental conditions; automatic control of 16 freeze-drying process flows; improved boiling and glass of freeze-dried materials The phenomenon has improved the efficiency and quality of freeze-dried products.

The project has been granted 8 patents and published 10 papers. In 2008, it received funding from the Ministry of Science and Technology's key new product plan project. In 2009, it won the Independent Innovation Silver Award at the International Scientific Instruments and Laboratory Equipment Exhibition and won the International Invention Exhibition Gold Award in 2012. At present, this achievement has entered the mass production stage and has been widely used in teaching and research, medicine, pharmaceuticals, food, environmental protection, monitoring, quality inspection, archeology, aerospace and many other fields, and has achieved significant economic and social benefits.

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